Iron
Συγγραφέας Αρετή Ρέγκλη Γράφτηκε στις ,
Iron is an essential micronutrient for all living organisms. To maintain the complex process of erythropiesis and heme synthesis erythroid precursors require 20-30 mg daily. The absorption of dietary iron is equal to the daily losses, so the most iron is available from senescent red cells. Ferritin and hemosiderin provide reserve of iron in the body. The functional iron consists of various proteins like hemoglobin and myoglobin. Binding to transferrin the iron is transported to sites of use. Iron intestinal absorption, circulation and tissue intake is tightly regulated at protein and cellular level. Hepcidin is a protein, primarily produced in liver and is regulated by iron status, inflammation, anemic conditions and hypoxia. In routine clinical practice the evaluation of iron metabolism is based on a combination of laboratory parameters, which help to establish the diagnosis and therapeutic procedures.
